You Are At Increased Risk For Oesophageal Cancer If You Get Flushed From Alcohol Consumption

Early-stage oesophageal cancer is often without symptoms. This makes it easy for us not to realise that something is amiss. Dr Kim Guowei, Senior Consultant Upper Gastrointestinal, Bariatric and Robotic Surgeon at Crest Surgical Practice, explained in a New Paper article (Flushed when drinking? There could be cancerous consequences, The New Paper 12 Feb 2018) that being flushed from alcohol consumption is a sign that you are at increased risk of oesophageal cancer.

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Symptoms Of Oesophageal Cancer

When symptoms of oesophageal cancer do show, they may include:

• Pain or difficulty when swallowing.
• Unintended weight loss
• Pain, pressure, or burning sensation in the chest.
• Indigestion and heartburn.
• Coughs or hoarseness.

Asians Are Genetically Predisposed To Getting Flushed From Alcohol Consumption – “Asian Flush”

The New Paper article highlights a third of Singaporeans are said to have a genetic predisposition to flushing, usually triggered as a result of alcohol consumption. In addition, two-thirds of them are unaware that condition results in an increased risk of cancer. In particular, of oesophageal cancer.

Flushing Is Caused By Genetic Mutation Resulting In An Enzyme Deficiency.

Dr Kim Guo Wei (then associate consultant in the Division of Surgical Oncology at the National University Cancer Institute), explained for the New Paper article that “alcohol is metabolised primarily in the liver via two major steps: conversion of alcohol to acetaldehyde and then to acetate. This process is regulated by enzymes.”

He explained further that about 40% of East Asians lack one of the enzymes needed to convert acetaldehyde to acetate. This increases the risk of cancer as acetaldehyde is a ‘probable human carcinogen’ (as classified by the US Environmental Protection Agency).

Flushing is the result of rapid accumulation of acetaldehyde in the body. It is not an indicator of drunkenness.

Alcohol Increasing Risk Of Oesophageal Cancer For People Who Experience Flushing

Doctors interviewed in the New Paper article says that people who experience flushing will increase their risk of oesophageal cancer if they continue to take alcohol. Studies have shown a strong correlation between the flushing condition and esophageal cancer. For instance, people with the condition who consumes two beers a day is “10 times more likely to develop esophageal cancer, compared with a (non-flusher) who drinks the same amount.”

Gastroscopy May Detect Stomach Cancer Early.

While there are symptoms of oesophageal cancer to watch out for, a gastroscopy is important for early detection due to the likelihood that the cancer is asymptomatic in the early stages. Those with greater risks such as a family history of oesophageal cancer can consider a gastroscopy to screen for the cancer.

Learn More: Gastrointestinal Cancer Screening

Consult A Doctor Or Surgeon On Your Gastrointestinal (including Oesophageal, Stomach, Colorectal) Health Or Cancer Concerns

Looking for a gastroenterologist or gastrointestinal surgeon to consult on your gastroscopy, colonoscopy, oesophageal, and other gastrointestinal health / cancer concerns? Contact us for help to arrange for an appointment.

This medical content has been reviewed by Dr Kim Guowei, a highly skilled upper gastrointestinal, bariatric and robotic surgeon known for his expertise in robotics and advanced endoscopic techniques. He offers comprehensive care for complex digestive disorders, from traditional open surgery to minimally invasive procedures.