Colorectal Cancer Screening Singapore – Colorectal cancer remains one of the leading cancers in Singapore, particularly among individuals aged 50 and above. Early detection significantly improves survival rates, which is why regular screening is highly recommended. Two common stool-based screening methods are the Faecal Immunochemical Test (FIT) and the Faecal Occult Blood Test (FOBT). While both detect hidden blood in the stool — a potential indicator of colorectal cancer — they differ in methodology, accuracy, and convenience.
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What Is FIT And How Does It Work?
The FIT is a more recent advancement in colorectal cancer screening. It uses antibodies to detect the presence of human haemoglobin (blood) in the stool. It is highly sensitive and only requires one sample, making it more convenient and user-friendly. Since FIT specifically detects human blood from the lower intestines, it reduces the likelihood of false positives caused by dietary factors such as red meat or certain vegetables.
Advantages of FIT:
- Higher sensitivity and specificity compared to FOBT
- No dietary restrictions before testing
- Requires only one sample
- Easier for patients to use and more hygienic
Disadvantages of FIT:
- Slightly more expensive than FOBT
What Is FOBT And How Does It Work?
The Faecal Occult Blood Test (FOBT), particularly the guaiac-based type (gFOBT), has been used for decades. It detects hidden blood in the stool through a chemical reaction. Unlike FIT, FOBT may react to animal haemoglobin from food, leading to false positives unless patients follow strict dietary restrictions before the test.
Advantages of FOBT:
- Widely available and low-cost
- Useful for mass screening in resource-limited settings
Disadvantages of FOBT:
- Requires dietary and medication restrictions
- Needs multiple stool samples over three days
- Lower sensitivity and higher false positive rate
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Contact UsColorectal Cancer Screening Singapore – Which Test Is More Common?
In Singapore, the Health Promotion Board (HPB) has endorsed FIT as the preferred method for national screening efforts under the Screen for Life programme. FIT’s greater ease of use and higher accuracy make it the more commonly used option in local clinics and hospitals. Its design encourages better compliance among the population, particularly for those above the age of 50.
What Is The Gold Standard For Colorectal Cancer Screening?
While FIT and FOBT are excellent initial screening tools, the gold standard for colorectal cancer screening remains the colonoscopy. This procedure allows direct visual examination of the colon and rectum and enables biopsy or removal of polyps during the same session. Colonoscopies are usually recommended for individuals at higher risk or after a positive FIT/FOBT result.
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